Objective To discuss the therapeutic effect of distal fixed modular femoral prosthesis for the hip prosthesis revision. Methods Between August 2004 and May 2008, cementless modular femoral prosthesis was used for hip prosthesis revision in 21 cases. There were 9 males and 12 females, aged from 49 to 72 years (mean, 64.6 years). The timefrom revision to total hip arthroplasty was 2 to 18 years (mean, 11.7 years). The causes of revision included aseptic loosening in 19 cases (5 cases were periprosthetic femoral fracture), and deep infection in 2 cases. First revision was given in all patients. Preoperative Harris score was 41.8 ± 3.5; pain visual analogue score (VAS) was 7.62 ± 0.86. Results All patients achieved heal ing of incision by first intention, and no deep venous thrombosis and nerve injury occurred. Twenty-one cases were followed up 2 to 6 years with an average of 4.3 years. No prosthetic loosening or infection occurred. Bone ingrowth was observed around the implant during the follow-up period. At last follow-up, 2 cases had femoral stem subsidence without obvious hip pain and other symptoms, and no special treatment was given. Harris score was 82.7 ± 3.3 and VAS score was 0.19 ± 0.51 at last follow-up, showing significant differences when compared with those before operation (P lt; 0.05). Conclusion The short-term result of modular femoral prosthesis is satisfactory in hip prosthesis revision, and it can improve the hip function and rel ieve the pain greatly.