Epilepsia is the official journal of the International League Against Epilepsy. This paper aimed to review and report the literatures published in 2024. A total of 348 articles were published in the journal Epilepsia in 2024, including 6 editorials, 41 critical reviews (systematic reviews and meta-analyses), 11 commentaries, 223 research articles, 31 brief communications, 30 others (including announcements, correspondences and corrections), and 6 special reports. Epilepsia is a journal focusing on epilepsy in clinical neurology, and the literatures published in 2024 are still dominated by clinical studies, although the number of randomized controlled trials is limitted. Chinese authors have published 10 original studies, some of which are important studies, and have contributed Chinese wisdom to the clinical and scientific research of epilepsy. In 2024, the editorials of Epilepsia reported first editor-in-chief in history from outside the USA and Europe, who advocated for strengthening cooperation with epilepsy organizations and associations around the world, promoting the continuous development and progress of Epilepsia.