ObjectiveTo analyze the research hotspots and progress of surgical treatment of myasthenia gravis. MethodsThe top 100 most cited articles on surgical treatment of myasthenia gravis were identified by searching the Web of Science database, and a bibliometric analysis was conducted. ResultsThe publication year of the top 100 most cited articles ranged from 1939 to 2021, and the number of citations ranged from 55 to 850 per article. Most of the included articles were original research articles (75/100), which were mainly retrospective studies (64/75). The United States was the country with the most published articles and most citations, and Annals of Thoracic Surgery was the most sourced journal (n=20). Through VOSviewer analysis, high-density keywords were thymectomy, maximal thymectomy, extended thymectomy, transcervical thymectomy, thymoma, and autoantibodies. ConclusionThe scope of surgical resection, surgical approach and pathogenesis are the current hotspots in the field of surgical treatment of myasthenia gravis. It is hoped that this paper can provide references for future researches in this field.
Objective To analyze relevant literatures of three-dimensional (3D ) imaging in liver using bibiometric analysis, and to provide a current status and hotspot in this filed in future for liver surgeon. Methods The bibliographies of liver 3D imaging from November 2007 to November 2017 in the PubMed database were downloaded. The publication years, journals, the first authors, and the frequency of subject headings+subheadings were extracted by Bicomb 2.0 software. The subject headings+subheadings appeared more than 10 times were intercepted as high frequency ones, then created the high frequency subject headings+subheadings co-occurrence matrix. SPSS 22.0 software was applied for clustering analysis with this matrix to get the topic hotspot. Results A total of 269 literatures were screened out. The research in this field reached its peak in 2016. The core area of journals contained 12 journals. There were 6 authors published at least 3 relevant literatures. The number of high frequency subject headings+subheadings was 16. The research hotspot of liver 3D imaging was precise liver surgery. Conclusion Research hotspot of application of 3D imaging in liver is precise liver surgery in recent 10 years.
ObjectiveTo analyze the current research status of radioactive iodine (RAI) therapy for differentiated thyroid cancer (DTC) in the past 10 years so as to understand the research hotspots and future development in this field through a bibliometric visualization analysis. MethodsThe literature relevant DTC RAI therapy published from 2014 to 2023 was screened using the Web of Science database. The publication time, country, institution, author, keywords, and other content of literature were analyzed, and the multidimensional scientific research network was constructed, and the visualization analysis was performed using RStudio and Flourish software. ResultsA total of 2 018 studies related to DTC RAI therapy were screened out from the publications from 2014 to 2023, with a fluctuating trend of increasing publication numbers. The publication numbers in China ranked first (422 articles), followed by the United States (374 articles) and Italy (182 articles). In terms of international cooperation, the United States ranked first with the most leading collaborations (289 times), and the top 3 countries in terms of cooperation with the United States were Italy (33 times), China (21 times), and France (21 times). China ranked fifth in leading cooperation, relatively less (52 times), with the main collaborators being Japan (7 times), South Korea (6 times), and Australia (5 times). Half of the top 6 institutions in terms of publication numbers were from the United States, with the top 3 being Unicancer from France (135 articles), Memorial Sloan Kettering Cancer Center from the United States (134 articles), and the UT MD Anderson Cancer Center from the United States (89 articles). Beijing Union Medical College Hospital and Shanghai Jiao Tong University ranked 19th and 23rd, respectively, with article counts of 46 and 44 articles. Tuttle RM, an author from the United States, ranked first in both publication numbers and contribution, with a total of 48 articles published from 2014 to 2023. There were two authors, Lin YS and Tan J, from China who had made it into the top 10 in terms of publication numbers, with 32 and 25 publications, respectively. The trend topics showed the evolution of hot topics, covering from the relation between urinary iodine and DTC, lymph node metastasis, to innovative research and prognosis assessment, as well as in-depth exploration of new therapies for iodine-refractory DTC. The co-occurrence and clustering of keywords included 4 aspects, namely, the standardized management of DTC, related contents during the peri-treatment period, papillary thyroid carcinoma, and the exploration of targeted therapy for iodine-refractory DTC. ConclusionsIn recent years, the research focus in the field of DTC RAI therapy has shifted from technical applications to management concepts, which has also promoted the improvement of treatment modes and made patients’ treatment plans increasingly personalized and precise. Future research will focus on precision medicine, individualized treatment, the combination of targeted therapy and immunotherapy, resistance mechanisms to treatment, and long-term management after treatment, aiming to improve patients’ treatment outcomes and quality of life and achieve a revolutionary breakthrough in treatment.
Objective To examine the research status and predict trends in ME research findings from 1997-2023 on a global scale. Methods Web of Science Core Collection database was searched for original articles on ME published between 1997 and 2023, and then analyzed using CiteSpace, VOSviewer and the Online Analysis Platform of Literature Metrology to map scientific knowledge. Results A total of 748 articles were eventually included. The number of ME publications increased year by year, with the USA being the most productive country. Osteoarthritis, MRI, medial meniscus posterior root repair, biomechanical evaluation, lateral meniscus allograft transplantation, radiographic joint space narrowing are the high frequency keywords in co-occurrence cluster analysis and cocited reference cluster analysis. Medial meniscus posterior root tear and lateral meniscus allograft transplantation are current and evolving research hotspots in citation burst detection analysis. Conclusions The understanding of ME has been improved significantly during the past decades. Current research focuses on optimizing surgical repair methods and obtaining long-term follow-up outcomes for medial meniscal posterior root repair and developing methods to reduce ME after lateral meniscal allograft, as well as they are the highlights of future research on ME.
Objective To review the literature written in English on hospital performance research and provide theoretical and practical references for research in the field of hospital performance in China. Methods Literature related to hospital performance published from 1972 to 2022 in the Web of Science Core Collection was retrieved. Microsoft Excel 2021 was used to analyze the annual publication volume of English literature in the field of hospital performance. CiteSpace 6.1.R6 software was used for co-occurrence analysis of countries/regions, institutions and authors, research hotspots and frontiers. Results A total of 1447 articles were ultimately included. The analysis of annual publication volume showed that the overall publication volume in the field of hospital performance was on the rise. The co-occurrence analysis of countries/regions indicated that the United States had the highest output of academic papers (548), followed by the United Kingdom and China (120 and 89 respectively). The most productive institution was Harvard University in the United States, and the most productive scholar was Harlan M. Krumholz from the Yale University School of Medicine in the United States. The most frequently occurring keyword was “care”. The clustering analysis of keywords revealed that the keywords in the field of hospital performance research were clustered into 12 categories. The top 5 keywords with the highest burst intensity included “acute myocardial infarction” “indicator” “US hospital” “predictor” and “administrative data”. Keywords such as “public hospital” “financial performance” “performance measurement” “framework” and “organizational performance” began to emerge in 2020 and had continued to the present. Conclusions The research hotspot in the field of hospital performance has shifted from focusing on individual performance to organizational performance. There is still a lot of room for research in this field in China, and the exploration of hospital performance evaluation and management models may continue to be research hotspots in this field in the future.
With the increasing global burden of various cancer, an abundance of papers emerged every year in the research hotspots of oncology, covering a wide range of research types and topics. In order to facilitate interested readers to quickly grasp the frontier and hotspots of cancer research, it would be helpful to sort out and summarize the research topic in a timely manner. According to the classification of disciplines, we screened the Essential Science Indicators (ESI) hot papers released in 2019 for the ones in the oncology field, utilized methods such as bibliometrics, statistical description, hierarchical induction, analysis and interpretation to further reveal the context and characteristics of research in the field of oncology, summarized the latest progresses and future directions in the field, and provided information and hints for the trajectory of future research. A total of 549 papers were included, which were mainly from the field of clinical medicine; the country with the most publications was the United States, while China ranked the fourth in terms of contribution; the research institution with the highest number of published papers was University of Texas system; N Engl J Med published the most papers, with contribution also from highly influential journals in the field of oncology such as Lancet Oncol, J Clin Oncol, JAMA Oncol and Cancer Discov. Oncology remained the most popular research topic in the medical research and spanned a wide spectrum of sub-topics. In this study, we demonstrated and sorted out research frontiers in the field of oncology in 12 different research directions including the basic cancer research, cancer epidemiology, and various tumors types related to different systems and organs.
Objective To analyze the research status of immunonutrition in China based on Chinese databases, and to provide a reference for clinical practice and future research. Methods Literatures about the application of immunonutrition in nutrition support were searched in China National Knowledge Infrastructure, SinoMed, Chongqing VIP and Wanfang databases using bibliometrics methods. The retrieval time was up to August 2022, and the document characteristics such as the number of publications, the institutions and the citation frequency and other features were analyzed. Results A total of 725 literatures were included, with the highest number of literatures issued in 2015 and 2020, both 62. The areas with the most published literatures were Jiangsu (10.6%) and Guangdong (8.4%). The institutions with the most published literatures were General Hospital of Eastern Theater Command (4.8%) and West China Hospital of Sichuan University (3.9%). There were 78 dissertations and 647 journal articles in total. The most published journal was Parenteral & Enteral Nutrition (6.5%). The top three citations were all reviews. The degree of cooperation was 2.7, and the co-authorship rate was 70.1%. A total of 121 articles reported the supporting funds and projects. The research types included 499 original studies (68.8%) and 226 secondary studies (31.2%). The analysis of the subjects showed that immunonutrition was mostly applied to gastrointestinal diseases, especially gastrointestinal cancer patients, accounting for 42.5%. Nutritional support was divided into enteral nutrition and parenteral nutrition. Enteral nutrition was adopted in most literatures, accounting for 88.4%. Conclusions The research content of immunonutrition in Chinese database in China is relatively simple. Most of them focus on the comparison between immunonutrition and general nutrition support. The selection of immune nutrients and the application of immunonutrition in critically ill patients such as sepsis need further research.
Objective To understand the research status of social network analysis methods in the medicine and health field, help medical scientific research managers quickly understand the publication situation and research hotspots of the methods, and provide references for them to use social network analysis methods to enter deeper research. Methods PubMed, Web of Science, Springer Link, ScienceDirect, China National Knowledge Infrastructure, Wanfang and VIP databases were searched for related literature on social network analysis methods in the medical and health field from the establishment of databases to April 2022. Bibliometric analysis was used to analyze the included articles. Results A total of 432 articles were included, with 424 in Chinese and 8 in English. The included articles were published between 1993 and 2020, involving 154 journals and 913 key words. The number of documents increased rapidly at first, and then entered a stable stage. The hot research directions were the spread and prevention of diseases and the power of social support networks. Conclusions Although the number of applications of social network analysis methods in the medical and health field has increased year by year and the application flexibility has increased, the application depth is still lacking. Scientific researchers should dig deep into the research direction, combine theory with practice, and focus on innovation.
Objective To discover the similarities and differences between CBM and MEDLINE databases in the field of post-earthquake health issue research characteristics in order to provide references and aids to the scientific research administration, professional education and training, research subjects selection and project finance support. Methods CBM and MEDLINE databases (from January 1987 to December 2009) were systematically searched to obtain literature about post-earthquake health issues. Those studies were classified and compared by the characteristics of research objects, health issues, research periods, and types of study design. Results A total of 701 literature from CBM and 387 from MEDLINE were included. MEDLINE database provided more studies focusing on victims of natural calamities with specific age description than CBM (Plt;0.05). Research peak of CBM database centralized in the period of three months after earthquake (n=645, 92%), while MEDLINE was three years after the earthquake (n=191, 87.2%). Studies from both databases similarly focused on physical trauma and psychiatric/psychological issues (two types of health issues in total: CBM: n=727, 86.1%; MEDLINE: n=358, 83.4%). Investigations from CBM were primarily designed for retrospective and descriptive research (n=439, 62.6%), cross-sectional investigations (n=146, 20.8%) and case report (n=86, 12.3%) while MEDLINE focalized on cross-sectional investigations (n=177, 45.7%) and retrospective and descriptive research (n=146, 37.7%). Conclusion Compared to MEDLINE, studies from CBM database are relatively weak in the post-earthquake health issues of population with specific age characters, long-term health issues, levels of evidence and types of research design. The possible reasons are insufficient attention to the post-earthquake health issues, inadequate preparation for the research or limited knowledge about research methods.
Objective To conduct a systematic bibliometric analysis of recent research on robot-assisted orthopedic surgery, in order to reveal the research trends, hotspots, main contributors, and future development directions in this field. Methods On August 27, 2024, WoSCC (Web of Science Core Collection Database) was searched and relevant literature on robot-assisted orthopedic surgery from 2003 to 2023 was included. Excel 2016, VOSviewer (version 1.6.10), and CiteSpace (version 6.2.R6) were used for data collection and analysis. Results The total citation frequency of 1718 retrieved literature was 28978 times, with an average citation frequency of 16.87 times per article. The total citation frequency of articles in 2019 was the highest (4330 times), and the publication volume in 2023 was the highest (315 articles). Among the top 5 countries in terms of publication volume, the United States had the highest publication volume and total citation frequency, while China ranked second in terms of publication volume, but had the lowest average citation frequency per article. Analysis of cooperation between countries showed that the United States, China, Germany, and other countries had the most cooperation. Babar Kayani’s articles were cited the most frequently. Among the top 10 institutions in terms of publication volume, the Hospital for Special Surgery (United States) had the highest publication volume, the Pennsylvania State System of Higher Education (United States) had the highest total citation frequency for publications, and the average citation frequency of each article published by the University of Pittsburgh (United States) was the highest. The dynamic evolution of research hotspots suggested that early research mainly focused on the combination of traditional surgical techniques and navigation, while in recent years, research had mainly focused on computer-aided surgery, augmented reality, and medical robotics technology. Conclusions In recent years, significant progress has been made in the research of robot-assisted orthopedic surgery, with the United States taking a leading position in this field and having extensive global cooperation. Research hotspots show that with the continuous development of computer-aided surgery, augmented reality, and robotics technology, the field of orthopedic surgery is evolving towards more precise, individualized, and minimally invasive directions.