Clinical Observation of Electro-acupuncture Combined with Oral Glucosamine Hydrochloride Capsules for the Treatment of Knee Osteoarthritis_West China Medical Journal

Authors：

 HUANGJian ¹ , YANGLi-wei ²

1. Traditional Chinese Medical Hospital of Zigong City, Zigong, Sichuan 643000, P. R. China;
2. The Fifth People's Hospital of Zigong City, Zigong, Sichuan 643000, P. R. China;

Corresponding author：

Keywords：

Osteoarthritis, knee; Electro-acupuncture; Glucosamine hydrochloride capsules

DOI：

10.7507/1002-0179.20140009

Video：

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Objective To observe the therapeutic effect of electro-acupuncture combined with oral glucosamine hydrochloride capsules in the treatment of knee osteoarthritis, and compare it with the curative effect of the two methods separately. Methods A total of 168 patients with knee osteoarthritis treated from March 2006 to December 2012 were randomly divided into 3 groups. Electro-acupuncture combined with oral glucosamine hydrochloride capsules were given to the 58 patients in the treatment group, single acupuncture treatment was given to the 57 patients in control group A, and simple oral glucosamine hydrochloride capsules were given to the 53 patients in control group B. The treatment lasted for 6 weeks. Assessment of knee osteoarthritis by Lequesne international standard index number and the total efficiency was carried out before treatment and 3 weeks, 6 weeks and 6 months after treatment, respectively. Results The total effective rate of the treatment group was 91.38%, of control group A was 68.42%, and of control group B was 79.25%. There was a significant difference between the treatment group and control group A, and between the treatment group and control group B (P<0.05). No blood, liver or kidney damage or gastrointestinal adverse reaction occurred among patients in all the three groups. Conclusion The efficacy of electro-acupuncture plus oral glucosamine hydrochloride capsules is better than simple acupuncture and simple oral glucosamine hydrochloride capsules treatment.

Citation： HUANGJian, YANGLi-wei. Clinical Observation of Electro-acupuncture Combined with Oral Glucosamine Hydrochloride Capsules for the Treatment of Knee Osteoarthritis. West China Medical Journal, 2014, 29(1): 30-33. doi: 10.7507/1002-0179.20140009 Copy

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1. 胥少汀, 葛宝丰, 徐印坎. 实用骨科学[M]. 3版. 北京:人民军医出版社, 2007:1337-1343.
2. 黎春华, 郭燕梅, 陈蔚, 等. 中文版Lequesne指数在膝骨关节炎评价中的评价者间信度[J]. 中国康复理论与实践, 2010, 16(6):554-555.
3. 徐卫东, 吴岳蒿, 张春才. 骨关节炎的诊断与治疗[M]. 上海:第二军医大学出版社, 2004:1-2.
4. 阙庆辉, 陈倩, 何锋. 针刺配合核心稳定锻炼治疗膝骨性关节炎35例[J]. 中国针灸, 2012, 32(2):143-144.
5. 中华医学会风湿病学分会. 骨关节炎诊断及治疗指南[J]. 中华风湿病学杂志, 2010, 14(6):416-419.
6. Takeuchi K, Tanaka A, Kato S, et al. Development of NSAID-induced small intestinal lesions-pathogenic role of COX inhibition[J]. Nihon Yakurigaku Zasshi, 2012, 39(3):103-108.
7. Bijlsma JW, Berenbaum F, Lafeber FP. Teoarthritis:an update with relevance for clinical practice[J]. Lancet, 2011, 377(9783):2115-2126.
8. 王哲, 方家, 付文轶. 硫酸氨基葡萄糖治疗膝关节骨性关节炎近期疗效评价[J]. 实用药物与临床, 2009, 12(6):397-398.
9. 张伟滨, 庄澄宇, 李健民, 等. 盐酸氨基葡萄糖治疗骨性关节炎有效性与安全性评价[J]. 中华外科杂志, 2007, 45(14):998-999.
10. 张超, 孟智宏. 针刺手法量学中时间与频率因素的研究进展[J]. 针灸临床杂志, 2012, 28(4):77-79.
11. 徐秋玲, 刘涛. 电针镇痛累积效应的疗效评价[J]. 上海针灸杂志, 2013, 4(32):289-290.
12. 余曙光, 郭义, 王瑞辉, 等. 实验针灸学[M]. 上海:上海科技出版社, 2009:133-135.
13. 刘源, 石桂秀. 骨关节炎的药物治疗进展[J]. 华西医学, 2012, 27(12):1761-1763.
14. 苏江, 张晶, 吴侗, 等. 盐酸氨基葡萄糖治疗膝骨关节炎的随机对照研究[J]. 华西医学, 2012, 27(12):1776-1779.
15. 张百挡, 梁祖建, 张还添, 等. 盐酸/硫酸氨基葡萄糖治疗膝骨关节炎的成本效果分析[J]. 中国组织工程研究, 2012, 16(52):9867-9872.

West China Medical Journal

Clinical Observation of Electro-acupuncture Combined with Oral Glucosamine Hydrochloride Capsules for the Treatment of Knee Osteoarthritis

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