• 1. Department of Colorectal and Anal Surgery, 940th Hospital of the Joint Logistics Support Force of the Chinese People’s Liberation Army, Lanzhou 730030, P. R. China;
  • 2. Northwest University for Nationalities, Lanzhou 730030, P. R. China;
  • 3. Gansu University of Traditional Chinese Medicine, Lanzhou 730030, P. R. China;
  • 4. Ningxia Medical University, Yinchuan 750004, P. R. China;
XU Ming, Email: drxuming@qq.com
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Objective To evaluate the short-term clinical outcomes of transanal total mesorectal excision (TaTME) for mid-to-lower rectal cancer and provide evidence for clinical decision-making. Methods The relevant literature from domestic and international databases in recent years was reviewed to systematically assess the current application of TaTME in the treatment of mid-to-low rectal cancer. A comparative analysis was conducted between the TaTME and laparoscopic total mesorectal excision (LapTME), focusing on intraoperative outcomes, short-term postoperative recovery, intraoperative and postoperative complications, oncological prognosis, and the learning curve. Results Conventional LapTME presented significant challenges in performing precise maneuvers within the pelvis and around the rectum, particularly in patients with “difficult pelvis” characteristics such as obesity, narrow pelvis, or male anatomy. In contrast, TaTME demonstrated certain advantages, including improved visualization of anatomical planes, reduced intraoperative bleeding, lower conversion rate to open surgery, faster short-term postoperative recovery, and enhanced specimen quality. Conclusion TaTME is a safe procedure with short-term outcomes, which is superior or comparable to those of laparoscopic surgery, offering a new surgical option for the treatment of mid-to-lower rectal cancer.

Citation: WANG Zhenning, ZOU Min, WANG Dechen, YANG Kang, GUI Mingbin, XU Ming. Current status and advances in clinical application of transanal total mesorectal excision for mid-to-lower rectal cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2025, 32(7): 895-902. doi: 10.7507/1007-9424.202412044 Copy

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